Fat Loss Just Changed, Forever.

0:00[Music]

0:00The weight loss game has changed

0:02forever. Some of you might remember a

0:03viral video I did where I had to stop

0:05taking a Zmpic only two weeks after

0:07starting it because I lost too much

0:08weight. But what a lot of people didn't

0:10see is about 3 weeks before that video,

0:12I posted another video saying why I

0:14hated ampic, why people should never do

0:16it, and that they should look really

0:18carefully at the side effects and

0:20negative consequences of these drugs.

0:22So, what changed? After I released the

0:23first anti-mpic video, there was a

0:25comment. The person said, "James, love

0:27your content, but you're wrong about

0:29these drugs. It quite literally saved my

0:31life." The only way to find out whether

0:32he was right or I was right was to take

0:34some glutide. And although nothing I say

0:35in this video is medical advice, it's

0:37important we understand it. What are

0:39weight loss drugs? What are GLP-1

0:41medications, what are people injecting

0:43into themselves? Well, the answer to

0:44that is a peptide. Now, I've done videos

0:46before about different peptide use. And

0:47for any of you wondering, a peptide is a

0:49short chain of amino acids. The first

0:50peptide I tried was something calledin.

0:53And that's something called a growth

0:54hormone secret. And people use that to

0:56increase their levels of growth hormone.

0:57That peptide gets your body to produce

0:59more indogenously rather than you

1:01injecting it externally. Indogenous

1:03means having an internal cause of origin

1:05and exogenous means having an external

1:07cause of origin. Now, I wouldn't use any

1:09of these at the moment because as I'm

1:10currently on TRT, for whatever reason or

1:12mechanism unknown to me, my growth

1:14hormone is incredibly high. And for any

1:15of you that are TRT curious, there's a

1:17link in the description called

1:18checkyoubloods.com. I'm on a mission to

1:19help men get their levels of

1:20testosterone checked. But anyway, one of

1:22the peptides that often comes within is

1:24something called CJC1 1295. And that

1:26helps with IPIN simply. They're often

1:28paired together. When you take them in

1:29the evening, you get a little bit of a

1:30hot flush. It's quite a nice feeling.

1:31Did I feel much of a difference? Not

1:33really. Then one of the most common

1:34peptides people talk about is BPC57,

1:36which is used to help people recover

1:37from injuries. BPC stands for body

1:39protection compound. Now, human clinical

1:41trial evidence to BPC57 is limited, but

1:44I have taken it. I tore my MCL in

1:46jiu-jitsu a year and a half ago, and

1:48although I would say it helped, that is

1:49anecdotal. That is not evidence because

1:51for me to actually have a standpoint of

1:53to the efficacy of BBC57, I would have

1:55needed a control which means I would

1:56have need to torn an MCL and not taken

1:58BBC57 and torn an MCL and taken BBC57

2:01and compared. It's worth noting that

2:03just because I was injecting myself with

2:04a compound that I would think would work

2:06would have had a massive impact on its

2:08own placebo and BBC57 is often paired

2:10with TB500 which is thomycin beta 4. And

2:13this helps with wound repair, muscle

2:15recovery and inflammation. Again, often

2:17when you get BPC57 and TB500, they are

2:19together. Some people think that the

2:21pills are best. Some people think the

2:22injections are best. For me, I don't

2:24know why I seem to think that if you

2:25inject yourself, just from a

2:27psychological standpoint, again, you're

2:28going to think it works better. The same

2:29reason that bottles of wine that are

2:31heavier, people perceive as more

2:32expensive. The way you administer

2:34something that you think is going to

2:35work has a massive impact. And if you

2:37don't think that the placebo effect is

2:39massive, all you need to do is look up

2:41something called a sham surgery. But

2:42quite literally, say someone's got a

2:44knee problem, you could put them under

2:45anesthetic, make an incision in the

2:46knee, stitch it back up, tell them that

2:48you fixed the knee, and there's a

2:49staggering amount of people that would

2:51recover from that surgery and go, "Wow,

2:52everything's fixed because they think

2:53it's going to be fixed." Same way that

2:55no SIBO effects. Anyway, we're getting

2:57distracted from the video. So, before we

2:58get to the new king in town, let's touch

3:00on to semiglutide to begin with.

3:01Semaglutide, the peptide name. It's also

3:03marketed as we go or their brand names.

3:06Now, my knee-jerk reaction was to hate

3:07this, probably because I'm a personal

3:09trainer. I have one of the world's

3:10largest coaching apps. For some of you

3:12that may or may not be aware, I've got

3:13an app called Affordable Online

3:15Coaching. For over 7 years now, we've

3:16had over 100,000 people use the app, and

3:18we've got people results like this,

3:19this, and even this. I'd love to say it

3:21was me, but it was actually my amazing

3:23coaches. We have memberships from £10 a

3:24month, and there'll be a link in the

3:26description where you can download the

3:26app. We give you a 7-day free trial. And

3:28if you think that I've broken any of my

3:29promises about this being a great app,

3:31there's a 2e money back guarantee period

3:32as well. So, if you're currently doing

3:33your own workouts, great. Ignore what

3:34I'm saying. and we'll get back to the

3:35video. But if you're someone that needs

3:36maybe a little bit of accountability,

3:38check out the app. Do the free trial.

3:39Thanks. Let's get back to the video.

3:40Straight away, I thought if this drug

3:41does everything, it's going to put me

3:42out of business. It's an insecurity.

3:44Same reason I'm wearing a hat cuz I'm

3:45going bored. It's an insecurity. And I

3:47often find that the majority of people

3:48online that are saying terrible things

3:50about these new medications, people that

3:52feel threatened by it. Two types of

3:53people. Those that make money from it

3:54and then people that have a certain

3:56amount of status from the way they look.

3:58For instance, the reason a six-pack is

4:00valuable is because not many people have

4:02a six-pack and it's very difficult to

4:03obtain, especially if you've got mid

4:05genetics. Same reason that people get

4:07hair transplant surgeries. To be in your

4:08late 30s and to have an impeccable

4:10hairline increases your level of status

4:12because people are making a snapshot

4:14decision at your levels of competence

4:15and people like to be good at things. We

4:17have hierarchies of who's better at

4:18what. It's why you have a belt system in

4:20jiu-jitsu. It's why any of you football

4:21fans will get giddy around a Premier

4:23League football player. It's all status.

4:24Now, people out there with incredible

4:26physiques, great hairlines, they get

4:28access to a lot of things in life cuz

4:30they look a great way. And it's good for

4:32them that the rest of the world is fat

4:33and out of shape. If you don't believe

4:35me, think about this. If you were to

4:36give someone a payriseise, it would make

4:38them happy. But if you were to give

4:39everyone in that department a pay rise,

4:40it wouldn't because it's not the payrise

4:42that makes them happy. It's them getting

4:43ahead whilst others remain behind that

4:45makes them happy. Any of you that have

4:47read this book by Will Store will know

4:49what I'm talking about. Status is around

4:50us everywhere. A lot of men, mostly

4:52those with good genetics, really hated

4:53the fact that when I started taking

4:55NTRT, I was a bit more jacked because if

4:56they're here because of genetics, and

4:58I'm there through administering small

4:59doses of testosterone, it means the

5:01rarity of their aesthetics are

5:03diminished, reducing its status. So, if

5:05you're someone that's a little bit dry,

5:06haven't got much personality, not much

5:08banter, but you look like a Greek god,

5:10and then suddenly other people are

5:11getting access to drugs that they can

5:13take without having to put too much

5:14effort in, you're going to feel

5:15threatened. Whether it's access to

5:16mates, whether it's engagement on social

5:18media, you are going to feel threatened.

5:20There's an interesting thing here where

5:21bodybuilders are now shaming other

5:22bodybuilders that are using GLP-1

5:24medications. They're saying, "You should

5:25suffer. You're cheating." And people are

5:27saying, "Hold on a second, but you're

5:28taking anabolic steroids." And they

5:30would argue, "Yes, but anabolic steroids

5:31give me the ability to suffer more. And

5:33with the dieting and chloric

5:34restriction, you should be suffering.

5:35You can't take steroids and a GLP-1

5:37medication and mitigate suffering on

5:39both sides." So, for any of you that get

5:40a knee-jerk reaction or people that

5:42really, really hate these drugs, it's

5:43more often than not a loss of status

5:45that they're worried about than anything

5:47else, not the actual drug itself. Now,

5:48in a snapshot, when I took a Zenic, I

5:50administered it on a Sunday night. I

5:52woke up the Monday morning and I felt

5:53nothing. I thought, I've obviously got

5:54the dose wrong. Maybe my maths isn't

5:56that good. Whatever it is, where did I

5:58make the mistake? It was only at lunch

6:00when I went to have a meal that I ended

6:01up putting half the meal back in the

6:02fridge, went to walk the dog, and it was

6:03only walking the dog that I was like,

6:04"Wa!" Never for my first meal of the day

6:07would I eat half and put half back. I

6:08was like, "Who was that guy?" And one of

6:10the things I concluded was although

6:11there was quite a bit of nausea from

6:12ampic semiglutide if I was to force down

6:15a protein shake or overeat at a meal

6:17sometimes it would feel a little bit

6:18nauseous. But as a net nauseous scale it

6:20wasn't that far more because most

6:22evenings at night I overeat. For me

6:24whenever I see people leave food on the

6:25plate I think they've got a mental

6:26illness. And for me unless I'm literally

6:29complaining about the amount I've eaten

6:30I've not eaten enough. So semiglutide

6:32for me was very interesting but the

6:33weight loss concerned me. So enter into

6:35the frey mangaro. Maro is a brand name

6:37for tisepide. And just before you all

6:39lose your as to James, why did you

6:42get this? It's a controlled drug.

6:43Earlier this year, I'd have hernia

6:45surgery. I was on the sofa one night and

6:46I was like, what's that in my belly

6:47button? And then I was like, hold on.

6:49This is my insides. Went to see a

6:50specialist. He fiddled around my belly

6:52button. He said, "Come back when it's

6:53worse." It got worse to the point that

6:54my insides would be sticking out my

6:56belly button. I couldn't push them back

6:57in. Gross. So, when I booked in to get

6:59the hernia surgery, I couldn't train.

7:00Didn't really feel like eating well. Sat

7:01on the sofa. How you all would if you

7:03were having to have surgery for acute

7:05injury. And my weight ballooned. And

7:07when I hit 100 kgs, I was like, I should

7:09do something about this. Now, I knew

7:11that I was going to be out of action

7:12where sofa bound for like a week and

7:14then not training for two months, maybe

7:16even 10 weeks. I knew I was going to get

7:18fat. So, I went through proper channels,

7:20qualified on the BMI to get my first

7:22dose of majaru. And here's a picture of

7:24just when I finished surgery. And then

7:25this is a picture about 10 weeks later,

7:27probably the leanest I've ever been.

7:29Now, here's something to really make

7:31clear. From a health perspective, not

7:32gaining weight was great, but from a

7:34mental health perspective, there's only

7:35two things that really balance my mental

7:37health on a daily basis. How I feel as

7:39far as physical looks and like strength,

7:41fitness, and how productive I am.

7:43They're the only two things. So,

7:44although I was working and filling my

7:45productivity cup, being injured, if I

7:47was a fat mess, it would have a massive

7:49impact on how I felt about myself, thus

7:51negating my mental health. So, to get to

7:53a 10-w week period after surgery, being

7:56in the best shape I've been in for

7:57years, having no instances of binging or

8:00gluttony, eating well, feeding my body

8:02what it needed to repair, and putting

8:04myself in a perfect position to start my

8:06rehab was amazing. And I'm allowed to

8:08say that cuz that's my own personal

8:09experience. And if I train today and

8:11blow my ACL, I will take these drugs

8:13again. If for whatever reason in my

8:15life, I'm going to gain weight and I'm

8:16going to become obese, there's two ways

8:18to balance your energy balance, to

8:20exercise more and to eat less. I've

8:21always joked around and said, "If your

8:22dog got fat, you wouldn't put it on a

8:23keto diet. If your dog got fat, you

8:25wouldn't give it slimming tea. If your

8:27dog got bloody fat, you take it for more

8:28walks and you give it less meals." But

8:30when I was injured, I didn't have the

8:31ability to walk more. I only had the

8:33ability to eat less. And considering

8:34that food is a place that I go to for

8:36comfort, for pleasure, all of those

8:37things, having a drug that meant I could

8:39be in control of that was massive. So,

8:41semiglutide, without getting too much

8:42into a science lesson, is a GLP-1

8:44receptor agonist. And topppatide is a

8:47dual GIP GLP receptor agonist. So just

8:50think about it in this way. Semaglutide

8:52works on one mechanism. Teptitide works

8:54on two. People on semiglutide lost about

8:5615% of their body weight. People on

8:58toeptide lost about 20 to 22% body

9:00weight. Toeptide always outperform

9:02semiglutide in head-to-head trials. Now

9:04one of the main concerns that people

9:05talk about these drugs is muscle

9:06wastage. Think about this. The majority

9:08of people taking these drugs are not

9:09fitness people. They are people whose

9:11other options would have been buriatric

9:13gastric bypass surgery where you cut

9:15people open and staple their stomach

9:16closed to get them to stop eating.

9:17People that are type two diabetic.

9:19people which are facing down obesity

9:22related diseases they're quite literally

9:23going to get premature death unless we

9:25get them to eat less. So when you look

9:26at observational studies across all

9:28these people, of course there's going to

9:29be muscle wasted. You just cut the

9:30calories in half. They don't train. They

9:31don't resistance train. For me, and keep

9:33in mind I am on TRT, the only thing I

9:35noted was an insane recmp. I didn't

9:37become weaker. I don't think I lost any

9:39muscle whatsoever. I wasn't doing DEXA

9:41scans. I wasn't doing measurements. But

9:42for me, when I looked in the mirror, I

9:44did not feel like I was getting smaller

9:45at all. I believe that through adequate

9:47protein and adequate resistance

9:48training, you can offset almost all of

9:50the muscle wastage. However, again, I do

9:52not have a control. Not on TRT. So that

9:54is a consideration to make especially

9:55when looking at my own transformation.

9:57So a rough difference is that this works

9:58on two mechanisms. Why it's better. I

10:00have no nausea on this. I do not feel

10:02sick at all. I barely notice that I'm

10:04taking the drug. If anything, when I

10:05take this, I feel like I'm meeting loads

10:08and my weight just carries on dipping.

10:09How much it costs? I pay about £250 a

10:12month. And again, I'm going through

10:13official channels to get that. As far as

10:14qualifying, you need to be over a BMI of

10:1730, which being 100 kg takes me to. So I

10:19wouldn't qualify for it now. I'm about

10:2194 12 kg. But one thing I would say,

10:23again, not medical advice, is anyone

10:25considering taking these drugs, try and

10:26find the lowest effective dose. Whether

10:28you're looking to lose weight, lose huge

10:30amounts of weight, what is the least

10:31amount of this drug you can take whilst

10:33getting the effects. I believe that in

10:35some places, some people are given

10:36dosages that are far too big. So, it's

10:37important that we look into side

10:38effects. Now, for me, although there was

10:40no nausea, there was one thing that I

10:41did not anticipate taking this drug.

10:43Whilst taking mangaro and semiglutide,

10:46you hate alcohol to the point even the

10:48thought of having a beer would make me

10:49feel sick. If anything, that was the

10:51only thing that returned my stomach,

10:52alcohol. And since stopping and

10:54discontinuing, I still have that

10:56relationship with alcohol. I very much

10:58struggle to drink now. So, if you were

10:59looking to lose weight, do not run these

11:02medications with alcohol. And that

11:04relationship to alcohol has carried on

11:05afterwards. I kind of miss being able to

11:07enjoy a beer at dinner. I just can't do

11:08it now. Again, it's personal anecdote.

11:10Now there are other side effects out

11:12there whether it's gastrointestinal so

11:14nausea, diarrhea, some people vomiting,

11:16constipation, some people can develop

11:18pancreatitis, acute kidney issues,

11:20gallbladder disease and all of these

11:22things can sound incredibly scary. But

11:23there are not many medications out there

11:24that come risk-f free. Even ibuprofen

11:27and paracetamol come with their own

11:28risks. Ibuprofen for instance that can

11:30reduce your kidney function, give you

11:31cardiovascular risk, can even give you

11:33stomach ulcers and bleeding. But we're

11:34not having that discussion when you're

11:36taking it for a rolled ankle. And the

11:37consideration that I don't think people

11:38are talking about online is there are

11:40side effects to taking weight loss

11:41drugs, but there are a lot of

11:42wellstudied side effects and

11:44life-threatening diseases that come from

11:46being obese. And for a lot of people

11:47that are going to start taking these

11:48drugs, they've got a choice. Potential

11:50nausea, potential vomiting, potential

11:51diarrhea, type 2 diabetes,

11:53cardiovascular disease, stroke. There

11:55could be potential side effects using

11:56GLP-1 medications. There are also a huge

11:59amount of side effects to being obese.

12:01So, we must look at this with a balanced

12:03opinion. These medications aren't just

12:04shortcuts. They're saving lives. They're

12:06improving people's mental health.

12:07They're improving people's physical

12:08health. They are reducing the burden on

12:09our health sectors. Not to mention this

12:12boom from the big short

12:13>> boom

12:14>> has already started. Obesity rates are

12:16already starting to decline. Jewelers

12:17are using less gold in wedding rings.

12:19Airlines are projecting to use less fuel

12:21over the next 10 and 20 years because

12:23passengers will be lighter. We could

12:24have potentially curbed the direction of

12:27the obesity epidemic and taken care of

12:28it for good. Not to mention, these drugs

12:31are only going to get better. And I know

12:33what a lot of you are thinking. When are

12:34we going to talk about ratutide? In

12:36another video once I've tried it.

12:37Semaglutide to zeppepide ratutide. These

12:40drugs are only going to get better and

12:41get safer and have bigger trials which

12:43means the landscape of controlling our

12:44levels of atapostity and obesity are

12:46only going to improve over time. And we

12:47should be excited by that. Even if it

12:49means that some of us fitness plebs

12:50aren't going to be quite so rare to

12:52having a good rig. It means that the

12:54majority of the world get to live in

12:55better quality and be happier,

12:57contribute more to society and be less

12:59of a burden to the state. And so many

13:01people that have given up on fitness,

13:02given up on weight training, given up on

13:03personal training, taller, you insecure

13:05personal trainers are going to find

13:06their way into the fitness industry and

13:07we should celebrate that. This is great.

13:09More gyms, more fitness locations, more

13:12paddle courts. The more people we get

13:14into the fitness industry, the better

13:15for all of us. I think only 16% of the

13:18UK have got a gym membership. Imagine if

13:19that goes to 30. Double the amount of

13:21gyms, double the sporting facilities.

13:23What? Because they used a weight loss

13:24drug, of which some of them are going to

13:25keep it off. And for some that rebound,

13:27oh, but it won't work forever. they can

13:28go back on the drug. Even if they're

13:30using this for three or six months of

13:31the year, it beats their current

13:32trajectory to what they're doing with

13:34their lives. Heaven forbid, touchwood,

13:35that tomorrow I was diagnosed with type

13:381 diabetes and I had to administer

13:40insulin every time I ate for the rest of

13:41my life. You would not create an

13:43argument with pharmaceutical industry

13:44and go, "Oh my god, it's terrible that

13:46James has to take insulin. He's

13:48dependent on insulin forever." Yeah,

13:49because if he doesn't take it, he'll

13:50die. For a lot of people who don't take

13:51these, they will also die prematurely.

13:53So although I do not like the

13:55pharmaceutical industry, although I do

13:57not like a lot of things, I get up

13:59when my son gets his vaccinations. I'm

14:01like, does he really need them? I'm as

14:02paranoid about big farmer as all of you,

14:04but that doesn't mean I can't still love

14:06these drugs and what they mean for

14:07people at the same time. Now, as these

14:09drugs get better and safer, I just want

14:10to explain something that you might not

14:12have thought about when it comes to

14:13weight loss. And for this, let's go to

14:15the whiteboard. This is the amount of

14:16time this is someone's weight. So let's

14:18say using a GLP1 medication, over time,

14:20someone's going to lose weight.

14:21Traditionally, as a personal trainer, we

14:23have had to motivate people for change

14:25here, getting to eat less, adhere to a

14:26calorie deficit, to eat better, to

14:28exercise, to train, hit a step count,

14:30all of those things. But with these

14:31drugs, we can now do those exact same

14:33things here. Because getting between

14:35here and here, the drugs help them eat

14:36better, help them understand portion

14:38control, help them say no to cravings,

14:40and help them feel more inclined to

14:41train to offset muscle wastage, etc.

14:43Where do you think it is easier to

14:45motivate someone to change their life

14:47when they're at their worst, fattest,

14:49heaviest, least healthy, least energy,

14:52least motivation, or at the healthiest

14:54they've ever been in a few years? Not

14:55everyone is going to be able to keep the

14:57weight off, but a certain percentage of

14:59people will. And it's because this is

15:01the point they're starting from, not

15:03here. Now, some people will lose the

15:04weight, they'll stop using the drug, and

15:06slowly over time, they will start to

15:07regain the weight. But this gives us

15:09time to identify why did this not work?

15:11Was it routine? Was it food prep? Was it

15:14exercise? We can administer the person

15:15the medication they need again and we

15:17can bring them down to another place.

15:18But the most important thing here is we

15:20can use these drugs. We, you and your

15:22doctor can use these drugs to keep that

15:24journey of you figuring out what it is

15:26you need to do to be fit and healthy and

15:28keep you out of the red zone where

15:30you're going to be much more inclined to

15:31be susceptible to developing things like

15:33type two diabetes, stroke, heart attack.

15:35Despite what people tell you on the

15:36internet, there are three ways that you

15:38can become more healthy. Lose body fat,

15:40become fitter, eat better. These drugs

15:42at first drastically reduce body fat. So

15:44even if the person doesn't eat better or

15:46exercise more, they are healthier

15:48objectively. However, these drugs also

15:50make it easier to eat healthy foods. You

15:53actually crave fruit and vegetables

15:54more. So the amount of rubbish foods

15:56that they're eating, the amount of

15:57inflammation they get from them is

15:59reduced. Then here's all of their

16:00excuses as to why they shouldn't

16:02exercise, hit 10,000 steps a day, and

16:03join a gym. And when you're eating well

16:05and you've lost a lot of fat, those

16:06excuses are diminished as well. Although

16:08these peptides can seem like just the

16:10drug to help you eat less, it's often

16:12the first domino of change necessary for

16:14someone to hugely change and transform

16:15their life. And I think it's important

16:16that we don't take those for granted.

16:17And anyone that's ever lost fat before

16:19will tell you it is so much easier to

16:21stay lean than it is to get lean. I hope

16:23you've enjoyed that video. In the link

16:24to the description, if you give me your

16:25email address, I can send you some more

16:27information about these medications and

16:28where the right places you should source

16:30them from. And if not, and you're

16:31someone that's potentially TRT curious,

16:33this video right here will probably be

16:34one of the best ones for you to

16:35understand more about what testosterone

16:36replacement therapy is like. And this

16:38video actually delves into all the

16:39terrible things about it.