Full transcript
0:00how does broken bone heal when the bone
0:04is broken that's called fracture the
0:08fracture goes through different stages
0:10to achieve healing
0:13it is a stage of hematoma from the
0:16fracture followed by a stage of
0:19inflammation followed by a stage of soft
0:22callus followed by hard callus followed
0:26by remodeling
0:29when the fracture occurs there will be
0:32bleeding at the fraction site and this
0:35will make a fibrin blood clot
0:39the stage of hematoma is followed by the
0:42stage of inflammation
0:44there'll be a lot of cells microphages
0:48and mesenchymal stem cells
0:52the stem cells migrate to the fracture
0:54and form the granulation tissue and
0:58releases growth factors that helps in
1:01healing the fracture and that helps in
1:04uniting the fracture together
1:07cox-2 Inhibitors and non-esteroidal
1:10depresses run X2 which is important for
1:14differentiation of the osteoblast
1:18the stage of inflammation is followed by
1:21the stage of soft callus
1:24soft callus will occur within two weeks
1:27the amount of callus correlates with
1:30immobilization the stiffer the
1:32immobilization the less amount of callus
1:37flexible fixation will result in
1:40endochondral ossification abundant
1:43callus
1:45what is secondary bone healing and what
1:48is primary bone healing secondary bone
1:51healing is healing through cartilage
1:53formation lack of stability helps the
1:57formation of cartilage which later on
2:00can change the endocondral ossification
2:04in primary bone healing you will find
2:07absolute stability and it's called have
2:11version remodeling cutting cone
2:13remodeling or intramembranous healing
2:17that occurs when the fixation is rigid
2:21and when the bone is fixed with plates
2:24secondary bone healing will occur when
2:27the fixation is not rigid such as with
2:31the cast or intermedullary rod and there
2:34will be endocardial ossification some
2:37cartilage type 2 collagen in primary
2:41bone healing will be type 1 collagen
2:43bone is formed first before cartilage
2:47then the bone takes number one collagen
2:50and the cartilage takes number two
2:52collagen
2:54stage of hard callus hard callus the
2:58collagen changes from type 2 to type 1.
3:03then the last stage is a stage of
3:06remodeling
3:08the stage of remodeling begins early and
3:12continues many years after the fracture
3:15has healed the woven bone will be
3:18replaced by a stronger laminar bone and
3:22the fracture healing will be complete
3:24with the continuation of the medullary
3:26canal
3:28the remodeling of the bone is influenced
3:31by the wolf's law that means that the
3:34bone is affected by stress
3:38so you start by stage of hematoma
3:41inflammation soft callus heart callus
3:45remodeling in this order
3:49thank you very much I hope that was
3:51helpful