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Marieb Chapter 6 part i

peter poon · 2,740 words · 13 min read

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0:02okay

0:03um so now we're moving on so you guys

0:07should have been done with your first

0:08exam

0:09uh hopefully that went well um so

0:12now let's move on to actually talking

0:14about modes so let me let me give you an

0:16intro to this

0:17module first this module

0:20actually has the most information okay

0:24so you probably need the most time

0:27studying um it's not physically

0:30difficult in terms of the type of

0:34information that i'm giving you but it's

0:36the most amount of information that i'm

0:39giving you

0:40um so be prepared okay

0:43um so you know start making flashcards

0:47um set aside more set aside more time to

0:51study

0:53um study with people okay

0:57watch the videos a couple times okay

1:00um that in particular regarding bones

1:03and muscles always helps

1:05okay and actually um

1:09a lot of things i i like to try and give

1:12you guys the news

1:13exercise when you exercise and um you

1:16actually do these

1:17exercises use these muscles that we're

1:19talking about when we talk about muscles

1:21it actually trains muscle memory okay

1:24you remember

1:24like you connect things you do with

1:28actual information and that actually

1:30helps a lot

1:31okay that being said let's start on

1:34chapter number six

1:39okay

1:43okay so chapter six

1:50okay so cartilage

1:54okay uh the basic structure of cartilage

1:57you already know

1:58right so uh location in basic structure

2:01cartilage

2:02uh cartilage is found throughout the

2:04body there is

2:07and you can see the model here okay

2:10the light blue is highland cartilage the

2:13green is um so the green is

2:17the green is elastic cartilage

2:21and the red is fibrocartilage so

2:24make sure you understand where all these

2:28three different types of cartilage

2:29are located and the differences in and

2:33how they're used

2:34okay so

2:38um all cartilage consists of something

2:43called perichondrium

2:45okay uh so like we talked about earlier

2:49cartilage has no no blood supply

2:53so the blood supply actually has to come

2:56the nutrients has to come from the

2:59perichondrium

3:00in okay uh so it functions in the growth

3:04or

3:05uh repair of cartilage

3:08okay because it's primarily a water

3:12okay cartilage is primarily water it's

3:14about 80 water

3:16and it's resilient so springs back to

3:18original shape

3:19okay after you compress it okay

3:22okay so all cartilages have something

3:25called a chondrocyte

3:27the chondrocyte are located within the

3:29unit and we can see the three different

3:32types of cartilage here

3:35okay okay

3:38so um a positional growth and

3:42interstitial growth

3:43okay a positional growth

3:46is the chondroblasts in the

3:49perichondrium

3:50producing new cartilage so let me show

3:53you how that works

3:55my new video okay

4:01so here's my piece of cartilage

4:08okay here

4:15okay is a perichondrium the

4:17perichondrium

4:20will generate

4:26new pieces of cartilage here

4:32okay so the newest cartilage will always

4:35be

4:37on the outside okay and that is

4:41a position a positional growth

4:44interstitial growth

4:52ammo circle

4:56okay so there's my piece of cartilage

5:04inside of my piece of cartilage is a

5:06chondrocyte

5:07that chondrocyte will divide into

5:14and what will happen is these two will

5:17grow new matrix

5:24okay so this one will grow more matrix

5:27so

5:27it will move

5:32further and that one will push

5:35further apart and because of this

5:41this piece of cartilage will get bigger

5:46okay interstitial growth growth from

5:50inside okay

6:02okay so this chapter is primarily about

6:05bone and how bones are formed

6:07okay uh bones contain several types of

6:10tissue

6:11okay but they're dominated by the the

6:13bone collective tissue that we saw

6:15okay but bone unlike cartilage

6:18has nervous tissue and has blood

6:22okay and has cartilage on the edges

6:32okay

6:34okay the functional bone bone provides

6:38um support okay provides movement

6:43provides protection okay so you know

6:46your skull

6:47right um your chest cavity okay

6:50it provides mineral storage it's a very

6:53important reservoir for important

6:54minerals and

6:56especially calcium and phosphorus

7:01okay um it it's involved with blood cell

7:05formation so

7:06the bone marrow right i'm sure you guys

7:08heard bone marrow before

7:10bone marrow form found within bone and

7:13bone marrow is responsible for

7:15formation of red blood cells and white

7:17blood cells

7:18[Music]

7:25okay

7:29all right bone is made out of two things

7:33okay so bonus is the only kind of tissue

7:36that is made out of a large

7:38percentage of inorganic components

7:41okay so bone has the organic components

7:44the cells the fibers the ground systems

7:46that you're very familiar with from

7:48every other tissue

7:49what makes bone different is that it has

7:52a large amount of

7:53inorganic components salts

7:56okay they invade the bone marrow matrix

8:00and make the bone matrix stiff and

8:03hard okay that's why bone is so hard

8:07okay

8:11okay so bone has exceptional qualities

8:1535

8:16is organic okay organic components

8:19contribute to flexibility

8:22okay it makes bones slightly

8:26bendable so um if you try to look at

8:29bone

8:30get it bowled off like a raw chicken or

8:32like raw

8:34cow um but not like cooked

8:37stuff okay the raw stuff is slightly

8:41bendable

8:41is it like you know put some pressure on

8:43the drumstick don't bend a little bit

8:45before it breaks

8:46that is the organic component of it

8:50okay it contributes to flexibility of

8:52tensile spring

8:56the inorganic components okay

8:59uh provide exceptional hardness and

9:02resist

9:03compression okay so let's

9:06take this apart so what would happen to

9:09bone if you didn't have the inorganic

9:12components

9:13the calcium okay the bone will become

9:16soft and i'll forward to the

9:19end of the chapter and i'll show you the

9:21picture what happens if you don't have

9:23enough

9:23calcium and i'm sure you guys have

9:25probably seen this before

9:27it's rickets

9:33okay the other thing that happens

9:37is the disease where you don't have the

9:40um organic components

9:43okay when you don't have the organic

9:48components

9:50okay when you don't have the organic

9:53component

9:56what happens is the bone becomes too

9:58stiff

9:59it becomes brittle it's like porcelain

10:03right

10:04it's hard but it breaks easily

10:07and that's what happens when you don't

10:10have the inorganic components

10:13okay uh or sorry when you don't have the

10:16organic components

10:17you have the stiffness of the inorganic

10:19components but now it's

10:20brittle and that disease

10:23is called osteogenesis imperfecta

10:27okay and you die of it either

10:30in like late in utero or early

10:34after childbirth okay um

10:37and they'll survive for more than one or

10:38two years

10:40again horrible thing we go through okay

10:46okay um there are three

10:49types of cells that help make

10:53bone okay

10:56they're called osteogenic cells

10:59osteoblasts

11:00and osteocytes osteogenic cells

11:04are stem cells okay that are going to be

11:08osteogenerating okay so

11:11genetic generate so these are both

11:14eventually formed both neither stem

11:16cells

11:16that eventually develop into osteoblasts

11:26okay

11:28okay um osteoblasts

11:34okay are not actively secrete

11:37osteoid osteoid is the

11:40gooey stuff that the osteoblasts secrete

11:44once the osteo oil is secreted it will

11:47harden and when it hardens it turns into

11:49solid foam

11:51okay

11:55cell osteoblast will secrete osteoid

11:58once the osteoid is formed around the

12:02osteoblast

12:03the osteoblast can't do anything anymore

12:06and it turns into a osteocyte okay

12:14the last type of cells that are found in

12:17bone

12:18are called osteoclasts osteoclasts are

12:21found within bone tissue okay they're

12:25usually on the inner edge or in the

12:26outer edge of the bone

12:28and they're responsible for reabsorption

12:30of the bone

12:32okay they absorb bone

12:36so one of the things you realize and

12:38we'll talk through

12:39is if you look like if you don't

12:42exercise

12:43you lose bone very quickly

12:49okay your your you might

12:52think like because a lot of things a lot

12:55of people think

12:56bone is like solid and never changing

12:59and it's dead material etc

13:01because you used to see it like

13:02picturing skeletons

13:05inside the human body your bone changes

13:09all the time okay

13:12if you put on muscle you put on bone

13:15if you lose muscle you lose bone

13:19okay so um

13:22putting on bone is going to be these

13:24three

13:25taking away bone is gonna be osteo class

13:28okay

13:32okay um classification of bones

13:36bones are classified based on their

13:39shape

13:39okay so look like if you picture a

13:42cartoon of a bone

13:44that's a long bone okay long bones

13:48are longer than they are wide and

13:50usually not even close

13:52okay short bones are going to be bones

13:56in the wrists

13:57okay or in the ankles okay

14:00so they're going to be like kind of

14:02squarish they're as long as they are

14:04wide

14:05okay and then flat bones are flat

14:08okay like they're sternum being an

14:10example okay your skull being another

14:12example

14:15okay all the bones in the skull are more

14:18or less flat modes

14:19okay and then you have irregular bones

14:22irregular bones

14:23don't fit any of the other four

14:25categories

14:28okay so your vertebrae um your hips

14:32okay all flat bones or sorry irregular

14:36bones

14:37okay

14:40so bone okay it's used for protection

14:45okay and therefore it has to be hard

14:48but the other people the other problem

14:50that people don't realize is

14:52bone has to be relatively light you

14:55don't want to be walking around 50 extra

14:57pounds of bone that you don't have to

14:59carry around

15:00okay that makes you slow right and that

15:04makes it

15:05harder to run away from lines and

15:07tighteners

15:09okay so what you want is a combination

15:12of

15:13good protection and being right and so

15:16the way they deal with this

15:27oops

15:30about that

15:38okay is to make a hollow circle

15:56okay the thick red line

15:59is going to be compact mode compact mode

16:02is extremely extremely dense

16:08okay spongy and then you're going to

16:11have spongy bone

16:13on the inside spongy bone

16:18is literally

16:22little tiny lines above

16:30and looks like sponge okay um

16:33that makes it hollow but strong

16:39okay let me show you how that looks like

16:48okay so

16:52compact mode spongy mode

16:56okay compact mode spongy mode

17:00okay

17:03okay um we're going to

17:07talk about the structure of a typical

17:09hormone that's one of the things you

17:11have to label

17:12okay so uh the diaphysis

17:16is the shaft of the bone okay the

17:19epiphysis are the ends of the bone

17:22and that bone labeling you guys have

17:24something in the middle called the

17:25metaphysis

17:26don't worry about labeling that okay um

17:30some books divide parts of the bone in

17:33three

17:34or the middle section and some don't

17:36okay

17:37it's just part of the epiphysis okay so

17:40just diaphysis epiphysis okay

17:44the bone is very well vascularized

17:46there's a lot of blood that goes to the

17:48bone

17:49okay and in the middle of the bone there

17:52is a measuring cavity that's filled with

17:55either red marrow or yellow marrow

17:57it adults that merrell is yellow and

17:59basically

18:00fat in children and especially

18:04babies that is red merrell and actively

18:07making red blood cells

18:09okay um

18:15there is a membrane okay there's two

18:18membranes

18:19that surround bone okay

18:23that's not about those two membranes

18:25okay

18:26so there's a membrane on the outside of

18:29the bone

18:30and that membrane on the outside is

18:32called

18:34periosteum peri means around perimeter

18:38right around osteum bone

18:42okay on the inside

18:46you have another membrane okay

18:49and that's called the indostium

18:52endo inside

18:55bone so endo osteo

18:58okay

19:06all right uh back to

19:10that show

19:15okay um

19:22we'll skip the structure of short bones

19:24okay

19:25um so bone desires and stress

19:29the anatomy bone reflects stress okay

19:33uh so here

19:36okay you can see how the stress changes

19:38your load comes down on your

19:40this is your femur this is your thigh

19:43bone the weight of your body

19:44comes down right on the head and femur

19:47and you can see

19:48that if you push down this way this

19:51area will become compressed and that

19:54area will be

19:55kind of bent out okay there'll be

19:58pulling on that side and compression on

20:00this side

20:02right in the middle right in between

20:04that the

20:05forces all cancel out perfectly

20:09and that means you have no force there

20:12that means you have no stress there okay

20:16and if you look there's

20:19no bone there where there is no stress

20:22you don't need bone if there's no stress

20:29okay the bone markings will skip for now

20:33um you can review these by yourselves

20:36okay

20:36um and we'll talk more about these

20:39things

20:40when we talk about these uh on the bones

20:43themselves

20:44like you need to know what a tuberosity

20:47is because

20:48i will ask you what the you know what

20:51the tuberosity

20:53is what the uh humeral tumerosity is

20:56etcetera

20:56etcetera etcetera okay

21:00uh okay

21:05okay so you guys can go through this

21:09by yourselves later okay the next

21:12example go over

21:13is the um

21:17microscopic structure of compact bone

21:20okay that's the other model that you

21:23guys have to really understand

21:25okay so let's talk about combat mode

21:28okay just because the compact bonus

21:30compact doesn't mean

21:32that there's no blood in fact there's

21:34special passageways

21:35for blood vessels nerves lymphatic

21:39vessels etc

21:40okay first of all um

21:44the osteon is the functional unit of

21:47compact mode okay so when we build

21:50compact mode

21:51we are building osteons when we tear

21:54apart compact mode

21:55we're tearing apart osteons

21:59okay okay

22:03um and these are the three ring

22:04structures you you saw

22:06in the uh tissue chapter

22:10okay okay osteon consists of

22:15the melee the central canal the

22:16peripheral canal and clinically okay so

22:19let's talk about the asean okay

22:26so this whole structure

22:29is a osteon okay this whole structure is

22:33the osteon

22:35a osteon is also called a perversion

22:37system

22:38okay in the middle of the ocean

22:42is a hole that hole is

22:45where the blood vessels run

22:51okay that hole

22:54is where the nerves arteries and blood

22:56vessels run and that hole will always be

22:59parallel to the length of the lung bone

23:06okay so that

23:09is the central canal see how it runs

23:12right along the length of the lung bone

23:14but the central canals have to talk to

23:16one another so there has to be channels

23:18that connect central canals and those

23:22are called the perforating canals okay

23:26because they porporate through the asean

23:29okay and so they're called perforated

23:32canals

23:32or the other name that most people use

23:35actually they're called

23:36volkman's canals okay named after vulcan

23:40discover them okay

23:43now let's go back to the osteon

23:47okay the osteon is made

23:50out of these concentric circles

23:54of solid bone the concentric

23:57circles of solvent bone are

24:00called la mele

24:05okay um

24:09so each one of these are called the

24:11ballet

24:12okay uh

24:15they're also called concentric lamellae

24:18because they run in concentric circles

24:21okay you also have

24:24solid bones that run all the way around

24:27the edge of the long bone

24:30okay those lamellae are called

24:35circumferential normally because they

24:37run they run around the circumference

24:41of the bone

24:45okay all right now let's take a closer

24:49look at the lamellae here

24:51the lamellae has little lacuna

24:56okay little lakes inside the little

24:59lakes

25:00there's a osteo site

25:03okay the two that like to the coolest

25:07two little osteo sites have to be able

25:10to communicate with one another

25:11so they're literally digging a channel

25:14through the bone

25:15to the point where they touch and that

25:18no channel through which they touch

25:20is called a candlelit choline

25:29okay those are catalytically

25:32or catalysts okay

25:35catalytically literally means small

25:38little canal

25:41okay all right um you probably want to

25:45replay this part at least once

25:47because you do have to know by all the

25:49parts of osteon so make sure you do that

25:51okay moving on

25:57okay so bone has

26:00collagen fibers embedded in the melee

26:03and the reason why the melee running

26:05concentric circles is

26:06one solid piece is because this way you

26:09have

26:10the collagen fibers running in different

26:12directions

26:13when you have the fibers run in

26:14different directions

26:16it is very hard to

26:19untwist them if they all run the same

26:23question

26:23direction you can just go between it you

26:25can just twist

26:26the same way and you'll untwist them

26:28this way because they run different

26:30directions there's no way to untwist

26:33okay okay

26:36real skip the spongy bone

26:40okay and we will stop right here

26:43and we'll pick up the part two um on

26:46part two of the presentation

26:54you

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