Full transcript
Introduction to Bone Health Success Stories
0:00All right, welcome back to the Dr. Doug
0:01Show. Today we have another success
0:03story for you. And what I like about
0:05this success story is that it actually
0:07took a little bit longer. This is a
0:09patient who really struggled early on.
0:10I'll talk about why she had some
0:12challenges, but we just continue to kind
0:15of work the program, figure out where
0:17the weaknesses were in the approach, and
0:19you'll see by the end that we were able
0:21to find success. So I look forward to
0:23sharing this with you and I want to
0:25define our structure as we go so that
0:27you can help to do this on your own. So
0:30what I'd like to do first is talk about
0:32how we approach creating a program for
0:34bone health. We use this thing called
0:36the 4R method which is just something
0:38that we created to help us to provide a
0:40framework for our patients but also our
0:43osteoclective members and anybody who's
0:45following us and helping us to kind of
0:48push this forward. We talk about this
0:494hour method a lot. So, let me just
0:51review it with you real quick. So,
0:53number one, the first R is to recognize
0:56why you're losing bone. This is just
0:59root cause medicine at its best. Why are
1:01we losing bone? We don't need to accept
1:03that bone loss is a part of aging. We
1:05prove that in our practice. So, why are
1:07you losing bone? Number one. Number two,
1:09the second R is then reverse those
1:12causes of bone loss. Now, when I talk
1:14about reversing osteoporosis, this is
1:16actually what I'm talking about. Yes,
1:18it's great to see that T-core go above
1:20negative -2.5, but what I'm actually
1:22talking about is reversing those causes
1:23of bone loss, improving your bone
1:25metabolism, and then you see improvement
1:27in your T- scores down the line. So,
1:29that's what I mean when I say reversing
1:31osteoporosis. The third R then is to uh
1:35retest and make sure that you're headed
1:37in the right direction. This is really
1:38really important and this is a good case
1:40example of that where she had a great
1:43program but it wasn't working initially
1:45because there were pieces that were
1:47still missing or weren't being done
1:48adequately. So while we had good initial
1:51labs, we thought we had the right
1:53approach, we ended up, you know,
1:55retesting and seeing, oh, we're not
1:57headed in the right direction. And so
1:59retest, make sure you're heading in the
2:00right direction. Don't just stick your
2:01head in the sand and assume that what
2:03you're doing is working. And then the
2:04fourth R is my favorite one and this is
2:06to revive your life and live without the
2:08fear of fracture. I'm going say it
2:09again. Revive your life and live without
2:12the fear of fracture. So that's the four
2:13R method. Again, easy for anybody to use
2:16this to apply their own uh tools into a
2:19framework to help improve their bone
2:20metabolism. Okay, so let's get back onto
2:22this patient. So uh we're going to call
2:24her Ruth. So Ruth is a 55year-old woman.
2:28She is 5'4 and 116 pounds. And this is
2:31pretty typical of our patient
2:33population. generally tend to be
2:35smallframed, underweight, undermuscled,
2:38and that is a recipe for osteoporosis
2:41eventually for a lot of people. Now,
2:43what made her case interesting out of
2:44the gate is that she also had a very
2:46strong family history. So, this is
2:49really important. If you have parents
2:51that had osteoporosis, if you had
The 4R Method for Bone Health
2:53parents that had fractures, it's really
2:55important to understand that you are at
2:57increased risk. In fact, I recently uh
3:00interviewed uh Dr. Stuart Kim who runs
3:02the company Axgen and this is he has a
3:04program that's all about identifying
3:06genetics for osteoporosis. I think
3:08mostly applicable to younger individuals
3:10to see what their risk is but this is
3:12another way to say it. Now in his test
3:15he shows I think it was over 80% of the
3:19uh future of your bone quality and
3:21quantity is based off of your genetics.
3:24That's a big number. So if you have a
3:26strong family history like this patient
3:28had both mother and father something you
3:30really need to pay attention to. Now
3:32before starting the program she had
3:34started doing a walking routine. She was
3:36walking three to four times a week but
3:38she had actually had a fracture right
3:40before this. So would that really
3:41changed the way that she exercised.
3:43Before that fracture though she was
3:45actually much more aggressive with
3:47running. So she was actually a runner.
3:49She would run four to five miles 5 days
3:52a week. That's a lot of running. And we
3:54know that running is associated with
3:56bone loss in a lot of people. So this
3:59may have been part of her cause right
4:01now. She was also at that time lifting
4:03three days a week and that's great. I
4:05don't have a lot of details of what that
4:06lifting included. So it's at least good
4:08that she was doing some resistance
4:10training at the same time. Now she also
4:11followed a vegan diet for many years
4:14through her adult life. And she actually
4:16said it really well in her own
4:17paperwork. She said, "I tried to eat a
4:20whole foods plant exclusive diet.
4:23However, I often times just ate more
4:25highly processed food and ate a quote
4:28glorified vegan diet. And that's what I
4:30see unfortunately a lot of people do
4:32because it's hard to eat a whole food
4:34plant exclusive diet. So, she was eating
4:37quite a bit of processed food and I
4:39think that was also probably playing a
4:41role in her bone health. Now, if we look
4:43at her DEXA scores, we actually have
4:45data going back four years. I don't have
4:46the official report going back, but if
4:49we go all the way back, her uh if you
4:51look back in
4:522022, her spine started at a T-core of
4:57-3.5. 2023 it was -4.1. So this is where
5:01she actually started having fractures.
5:02She's had multiple fractures. Um so this
5:05is a really bad starting point. Right
5:07now her hips were a little bit better,
5:08T-core of -2.6 and they stayed at -2.6
5:12as she went from 2022 to 2023. So, her
5:15spine was her biggest concern. So, I
5:17have her entire list of supplements when
5:19she started the program with me, and I'm
5:21not going to list them out because it's
5:23a really, really long list. And what I
5:24want to point out here is that she was
5:27doing what she thought were all the
5:29right things. Now, she was doing weight
5:30bearing exercise. She was walking 3 days
5:32a week. She wasn't doing any any
5:34resistance training yet because she was
5:36she was recovering from a spine
5:37fracture. Um, but this list of
5:39supplements is massive. So, I'm just
5:40going to list off a couple things. I'm
5:41not going to go through all of it here,
5:43but she was on D3 K2, she was on an
5:46omega-3, she was on a mag glycinate, she
Case Study: Ruth's Journey
5:49was on methylated B12, she was on a
5:51probiotic, she was on a osteo combo
5:55product, she was on estragalus,
5:58iraflavon, she was on a couple of kidney
6:01things, she was on a couple of metabolic
6:03things, she was using borage oil, some
6:05vitamin E, some other minerals. Um, just
6:09looking at this list, it's massive. Uh,
6:13amazing grass green blend, melatonin,
6:16torine, and on and on and on. Collagen.
6:19So, she had this really massive
6:21supplement list, and we see this pretty
6:23frequently. She was doing weight bearing
6:25exercise, but she was still losing bone.
6:27Now, she was also in a bad starting
6:29point because she has now had multiple
6:31fractures. She's had multiple rib
6:33fractures, which are not technically
6:34fragility fractures, but one was from
6:36her husband hugging her.
6:38H that's a low mechanism force right
6:41there. Um the other one was from a dance
6:43partner picking her up on her ribs,
6:45right? And caused a rib fracture. Now
6:47she had some spine fractures from
6:48falling down the stairs. That's
6:51potentially real trauma, but actually a
6:53fragility fracture depending on the
6:55mechanism. And then she also had the
6:57most recent fracture in 2022 uh from
6:59riding a horse. So she's had multiple
7:01fractures. She has low bone density.
7:04This is a bad starting point. Now, when
7:06we first met and we talked about all of
7:08the different approaches, for us always
7:10hormone optimization comes up. Now, she
7:13has an interesting family history that I
7:14want to talk about because for her, this
7:16was really the biggest driver of her not
7:18using hormones. So, her mother died at
7:21the age of 70 of a recurrent metastic
7:24breast cancer that was initially
7:25diagnosed at the age of 47. Now, you can
7:27imagine this impacted her significantly
7:29as she went through menopause and had a
7:31conversation around hormones. her
7:33doctors, as she told me, told her that
7:35she had a strong family history and that
7:36it was too dangerous to use HRT. Now,
7:39here's what's frustrating about that.
7:40So, number one, they didn't take into
7:42account that she already had low bone
7:44density and osteoporosis. So, she
7:46literally was in a position of increased
7:48risk of another disease that was going
7:50to get worse with estrogen deficiency.
7:54Secondly, the risk of cancer,
7:58specifically breast cancer that comes
8:00from having a family member with an
8:02increased risk or with a history of
8:04breast cancer is already present. So
8:07that risk doesn't change whether or not
8:10she uses HRT or not. And this is
8:12misunderstood. So I'm going to say that
8:13another way. If you had a family member,
8:16immediate family member, sister, mother
8:19that had an early cancer, it puts you at
8:22increased risk of developing cancer.
8:24That's true. That's the genetic side of
8:26it, even if there were lifestyle factors
8:29involved. But that risk already exists
8:33prior to the decision to start HRT. And
8:36the risk doesn't change when you start
8:38HRT. This is what's misunderstood about
8:41family history. Now, that does mean that
8:43we do need to be more cognizant of
8:44screening. We need to be more aware that
8:46you are at higher risk and hit
8:48potentially, especially if not done
8:50right, could make a cancer grow faster.
8:52So, I'm not saying it's not relevant,
8:53but it's not a reason in my opinion not
8:56to start, especially like in this case
8:58where some of the, you know, more common
9:00cancer genes had actually already been
9:01ruled out. Sorry to pause this success
Understanding Hormone Replacement Therapy
9:04story, but if you are struggling to find
9:07your own success story, you're looking
9:08for more information, please consider
9:10coming to our free master class. The
9:11master class we do about every other
9:13week. I run it myself and we talk about
9:16the top uh I think it's three or maybe
9:18five at this point um mistakes that we
9:21see people making as they are creating
9:22their bone health journey. It's very
9:24very consistent. We see people make
9:25these same mistakes all the time and I
9:27don't want you to do that. So come join
9:29us. We'll talk about the things that
9:30we've seen and then we also leave about
9:3220 minutes for Q&A. We talk about some
9:34resources on where to potentially go
9:36from there. It's totally free. Look for
9:37the link in the description on YouTube
9:39or you can head to our website
9:41optimalhumalth.com and you can find it
9:42there as well. Okay. So, how do we do
9:44this? Well, we want to start with the
9:46four Rs, right? So, what is the reason
9:49why she's losing bone? Let's recognize
9:50why she's losing bone. Well, we already
9:52said some of it. She had a sedentary
9:54lifestyle because of a fracture. She was
9:56eating a vegan diet. When we started
9:57tracking her protein, she was getting
9:59nowhere near ideal protein. We're
10:01talking 30 to 40 grams a day. So, that's
10:04a clear reason. She also had some gut
10:05dysfunction, which I haven't talked
10:07about yet. Um, she wasn't on hormones
10:09and she was early in menopause, right?
10:11So, she's 55 years old. I think she went
10:13through menopause in the her early 50s.
10:16So, we're talking like within the first
10:17two to three years. And we know that
10:19you're going to rapidly lose bone during
10:21that time frame. Okay. So, then what do
10:22we do with the second R? How do we
10:24reverse then those causes of bone loss?
10:26Well, we had a conversation around HRT,
10:29right? So, this is one of the biggest
10:30tools you can use. So, we started her on
10:33HRT. We educated her on the risk and we
10:35educated her on the best ways to do
10:37screening. And she was very comfortable
10:39with that. And she feels great on HRT.
10:41Now, the other big player for her is
10:43going to be diet. So, we dug into the
10:45reasons. Why are you eating a plant
10:48exclusive diet? Why are you avoiding
10:50animal products? And it turned out there
10:51were some animal products that she was
10:53actually willing to consume. and there
10:55were some animal products that she
10:56wanted to avoid. So, we found a way to
10:58get more protein for her in a way that
11:01she was comfortable with that aligned
11:02with her morals, her values, and um her
11:06views on animal husbandry. So, we were
11:08able to start getting her more protein.
11:09She's tracking. She's getting over 100
11:11grams of protein a day. That was a
11:13massive change for her diet. The
11:15exercise part is an area where we really
11:17struggled because she was recovering
11:19from this vertebral fracture. She was
11:21walking. She wasn't doing any resistance
11:23training. She had a history of it but
11:25was afraid of it and rightfully so. So
11:28we started her with some light
11:29resistance training. We have a
11:30four-phase program. She was in phase
11:32one. It's a lot of body weight movement
11:34getting used to uh technique again. She
11:37did some of this with a weighted vest.
11:39She was able to wear that with her spine
11:40once it was healed. And then she also
11:42did osteogenic loading through a
11:44biodensity power plate like device. We
11:46went through a gut health program with
11:48her as well. Uh but those were probably
11:50the biggest factors that we put into
11:51play. I wanted to mention a little bit
11:53too about her HRT because I know there's
11:55lots of questions around how, you know,
11:56how do we do it? What's the best way to
11:58do it? And I can tell you that the best
11:59way is going to be individualized. Um,
12:02this particular patient, by the time she
12:04was done with us, she was on a 4
12:06milligram per ml estradile cream twice a
12:08day. She was using DHEA as well as some
12:12testosterone. Uh, of course,
Dietary Changes and Protein Intake
12:14testosterone is off label uh for any
12:17woman. And then she was on progesterone
12:19and we were able to titrate her up to
12:20300 milligrams at night. So this helped
12:23her with her sleep. She felt great. She
12:25had better energy. I mean she was just
12:28raving about how she felt on her
12:30hormones. Now what's interesting we'll
12:31talk about at the end is that we are
12:33still not actually to goal if you look
12:35at her serum levels. But that's okay
12:37because I'll show you all the other
12:39things and it's everything's definitely
12:40headed in the right direction. So we
12:42changed up her supplement stack. And in
12:44fact, for her, and this is actually not
12:46not that uncommon for her, we actually
12:48reduced the number of supplements that
12:50she was on. So, we put her on a couple
12:52of things for detox. She's on a specific
12:54K2. She's on something for um estrogen
12:57metabolism. We did some some urat
12:59metabolite testing on her. She's on
13:01Tongad Ali to help to with conversion of
13:04the testosterone that she's getting into
13:05free testosterone. That was an upgrade
13:07we have to make. Over time, she's on
13:09some additional magnesium. She's using a
13:12product for thyroid support. She using a
13:15product for cortisol support. She's on
13:17lactoerin, lipidrol ox, which is a a
13:20great product that helps with both
13:21oxidized LDL as well as um uh bone
13:25health. She's on a a B complex uh
13:28continued on a fish oil and then algical
13:31plus and this product cardio NAD. Uh she
13:34has a lot of concern around
13:35cardiovascular risk. So still a
13:37substantial list, right? Uh but we're
13:40hitting a lot of things. There's a lot
13:41of cardiovascular, there's a lot of
13:42detox. There's actually not that many
13:44things in there that are specific for
13:45her bone
13:46health. Okay, so how do we do? Let's
13:50fast forward two years. Now, I said
13:52early on we had struggles, and we did
13:53because it was a struggle to get the
13:55right food. We had to do some gut work
13:57to be able to get all that protein in
13:59because her gut just wasn't used to it.
14:00It wasn't used to eating animal products
14:02at all. Right? So, we had to do some gut
14:04work. She worked with our dietitians.
14:05Uh, so that took some time. exercise was
14:08really slow to get going because she had
14:10that fracture and she had a lot of fear
14:12around lifting. So we started at a
14:14pretty low level and we progressively
14:16overloaded and that takes time if you
14:18have a very uh low starting point. So we
14:22have now DEXA so actually two years
14:24later. So we started her DEXA journey in
14:272022 and now we have data for the
14:29subsequent four years. I told you her
14:31spine went from 35 to 41 before she
14:33started working with us. uh within her
14:35first year she went from 41 to 37
14:38negative uh 37 as a t-core which is a
14:41good improvement but the next year she
14:43went from -37 to -31 and so now she went
14:47from -41 to -31 I only have the bone
14:50mineral density numbers for the last
14:53that jump from 37 to 31 and that's a
14:569.8% an 8% improvement in 1 year. Now,
14:58obviously, it's bigger if you go from
15:004.1 to 3.1, but when you're doing
Progress and Results Over Two Years
15:03percentage change, this is really
15:04important. When you're doing percentage
15:06change, you have to use the bone mineral
15:07density, grams per centimeter squared,
15:10versus the um uh t-core. So, if you do
15:13the math on the t-core, you'll get these
15:15kind of big wonky numbers. And remember,
15:16that t-cores change even if your bow
15:19density stays the same, which is a
15:21confusing topic. So, anyway, over that
15:23last year, around 10%. Now her hips just
15:25a little bit slower. Again, I only have
15:27the last year and that was a 7.4%
15:30improvement. She went from 26 to 25 and
15:32then -25 to -22. So she's actually out
15:35of the osteoporosis range uh for her
15:37hips and I think she will be with her
15:38spine probably over the course of the
15:40next year. All right. So then how did we
15:42do that? Well, let's think about it
15:44again. So we used the 4R method. We
15:47identified that she had genetics working
15:49against her. She had her diet working
15:50against her. She had her exercise
15:53working against her. her hormones
15:54working against her, her gut, and her
15:56stress, which I didn't talk that much
15:57about. So, if we're talking about the
15:59first are recognize why you're losing
16:02bone, that's the lowhanging fruit.
16:04That's what we aimed for. And then we
16:06created a program to address as many of
16:08those as we can. But here's what I want
16:10to point out about this case. You know,
16:12if we look at what we did with her, we I
16:15don't want to say we struggled, but it
16:17took us a lot of time to get things
16:19moving in the right direction. That's
16:20why she was with us for two years. But
16:22even if I look at where she is at the
16:24end of two years, it's still not perfect
16:26by any means, right? There's still room
16:28for improvement. Her hormone levels
16:30aren't that high. Her FSH is still 70.
16:32It was 100, so it's better. Um, but her
16:36hormone levels still aren't ideal when
16:38it comes to her labs. Now, she feels
16:40great, but we know that we need to look
16:43at other things, too. Her bone turnover
16:45markers did continue to improve. They
16:47were kind of went up and down throughout
16:48the program, and at the end, they were
16:50still over 150. Clearly, she's building
16:52bone. I'm happy with that. We wouldn't
16:54necessarily have to change anything, but
16:56I still think she could be more
16:57optimized. I think she could be doing
16:59more with her exercise, too. So, there's
17:01still room for improvement. And the
17:02reason why I bring this up is because it
17:05doesn't have to be perfect. You just
17:08have to find the lowhanging fruit, the
17:09things that are going to give you the
17:10biggest impact. Address those things as
17:13well as you can, and then retest and see
17:15if it's enough. And if it's not, then
17:17you need to recalibrate. And if it is,
17:19keep going. and then keep retesting and
17:22make sure that it's still working. It
17:24doesn't have to be perfect. And that's
17:25the takeaway from today. So that's it.
17:27Remember that a diagnosis of
17:28osteoporosis isn't the end, but deciding
17:30to reverse it is the beginning. I'll see
17:32you in the next video.